|DISEASES AND CONDITIONS
|New diabetes guidelines imminent, Jardiance sales may surge
<p><a href="http://news.yahoo.com/diabetes-guidelines-imminent-jardiance-sales-may-surge-204255226--finance.html"><img src="http://l.yimg.com/bt/api/res/1.2/8OulPelG6BbDeGieo3WDyg--/YXBwaWQ9eW5ld3NfbGVnbztmaT1maWxsO2g9ODY7cT03NTt3PTEzMA--/http://media.zenfs.com/en_us/News/Reuters/2016-12-09T204255Z_1_LYNXMPECB81FO_RTROPTP_2_ELI-LILLY-DIABETES.JPG" width="130" height="86" alt="A screen displays trading information for Pfizer, Abbott Laboratories, Merck and Eli Lilly and Company on the floorof the NYSE" align="left" title="A screen displays trading information for Pfizer, Abbott Laboratories, Merck and Eli Lilly and Company on the floorof the NYSE" border="0" /></a>Two leading U.S. medical societies are poised in the coming weeks to issue new diabetes treatment guidelines reflecting the lifesaving cardiovascular effects of Eli Lilly's Jardiance in a move expected to drive up the drug's sales. The forthcoming guidelines from the American Diabetes Association and the American Association of Clinical Endocrinologists follow last Friday's decision by U.S. regulators to expand the health benefits Lilly can claim for Jardiance to include preventing fatal heart attacks and strokes in type 2 diabetes patients.</p><br clear="all"/>
Anxiety, irritability may precede depression in high-risk teens
By Lisa Rapaport (Reuters Health) - When parents have a history of depression, teens are at greater risk for developing the disorder themselves, and signs of being irritable, anxious and fearful may precede a first episode of depression, a recent study suggests. Other things, like low mood and disruptive behavior, don’t appear to come before the onset of major depression for teens with a family risk for the disease, the study also found. “Risk processes in our study of children at increased familial risk for depression look quite similar to what is found in the general population – poverty, recent stressors, early clinical symptoms in the child and the degree of familial risk for major depression all contributed to the likelihood that a child or teen would develop major depression in our study,” said lead study author Frances Rice of Cardiff University in Wales.
Mother of One Direction singer Tomlinson dies from cancer
<p><a href="http://news.yahoo.com/mother-one-direction-singer-tomlinson-dies-cancer-181724500.html"><img src="http://l1.yimg.com/bt/api/res/1.2/SzgKnMEwAoo7kfbk4vfIzQ--/YXBwaWQ9eW5ld3NfbGVnbztmaT1maWxsO2g9ODY7cT03NTt3PTEzMA--/http://media.zenfs.com/en_us/News/Reuters/2016-12-09T182048Z_1006970001_LYNXMPECB81CC_RTROPTP_2_CENTERTAINMENT-US-PEOPLE-LOUISTOMLINSON-MOTHER.JPG" width="130" height="86" alt="Singer Louis Tomlinson of the band One Direction performs on ABC's Good Morning America inside Central Park in New York" align="left" title="Singer Louis Tomlinson of the band One Direction performs on ABC's Good Morning America inside Central Park in New York" border="0" /></a>LONDON (Reuters) - One Direction singer Louis Tomlinson's mother has died from an aggressive form of leukemia, her family said on Friday. Johannah Deakin, 43, who worked as a midwife and had seven children, died on Wednesday in hospital in Sheffield, where she had been since May after being diagnosed with the cancer. Tomlinson, Deakin's oldest child, is scheduled to perform at the final of British television singing contest "The X Factor" at the weekend, British media reported. ...</p><br clear="all"/>
Better aerobic fitness may reduce men’s risk of cancer death
By Shereen Lehman (Reuters Health) - The better a man’s cardiorespiratory fitness, the less likely he is to die from cancer, suggests a long-term study from Denmark. Cardiorespiratory fitness is a measurement of how well the body uses oxygen during intense exercise. Good cardiorespiratory fitness is well known to be associated with better cardiovascular health, but less is known about its effect on cancer risk, the study team writes in the British Journal of Sports Medicine.
More pilot mental health checks, alcohol testing on cards under EU proposals
The European Commission will propose legislation next year requiring airlines to run mental health checks on pilots before they start commercial flying, as part of efforts to prevent a recurrence of last year's Germanwings crash. Authorities have been looking at ways to toughen pilot screening and better assess their mental health after a young pilot locked himself in the cockpit and crashed a Germanwings plane into the Alps in March 2015, killing all 150 aboard. Under the new proposals, put forward by the European Aviation Safety Agency (EASA) on Friday, operators will have to ensure pilots have access to support programs.
Astra, Lilly stick with Alzheimer's approach despite setback
<p><a href="http://news.yahoo.com/astra-lilly-stick-alzheimers-approach-despite-setback-132759240--finance.html"><img src="http://l3.yimg.com/bt/api/res/1.2/c01PXuAwsIyJK2EKl6jsFQ--/YXBwaWQ9eW5ld3NfbGVnbztmaT1maWxsO2g9ODY7cT03NTt3PTEzMA--/http://media.zenfs.com/en_us/News/Reuters/2016-12-09T132759Z_1_LYNXMPECB80XJ_RTROPTP_2_ASTRAZENECA-PFIZER.JPG" width="130" height="86" alt="A sign is seen at an AstraZeneca site in Macclesfield" align="left" title="A sign is seen at an AstraZeneca site in Macclesfield" border="0" /></a>By Ludwig Burger FRANKFURT (Reuters) - AstraZeneca will expand its collaboration with Eli Lilly to develop an experimental Alzheimer's drug, sticking with an approach that has been a mainstay of research despite recent setbacks. Astra said it would team up with Lilly to develop a drug known as MEDI1814, currently being tested on humans in the first stage of development. It is designed to prevent a protein called beta amyloid from forming plaques in the brain, which is believed to play a pivotal role in Alzheimer's. Last month, the failure of Lilly's experimental drug solanezumab to slow cognitive decline cast doubt on this approach to fighting the debilitating disease.</p><br clear="all"/>
Further promising data seen with Biogen Alzheimer's drug: study
(Reuters) - Gradually increasing the dose of Biogen Inc's experimental Alzheimer's disease drug appeared to reduce the risk of brain swelling compared to higher fixed doses, interim 12-month results from a small study released on Thursday showed. "These data appear solid to us, and if anything provide additional confidence in the program and viability of the titration regimen," Evercore ISI analyst John Scotti said in a research note late on Thursday. In the group of trial patients given titrated dosing, 35 percent experienced a side effect involving a fluid shift in the brain, compared with 55 percent given a high fixed dose, Biogen said.
Athletes may need to work more than the rest of us to avoid the flu
By Lisa Rapaport (Reuters Health) - Athletes who cram in extra workouts over the holidays to avoid packing on extra pounds also need to take extra precautions to avoid getting sick, recent guidelines stress. "Sudden increases in training and competition load can increase the risk of illness," Schwellnus, a sports medicine researcher, said by email. The picture is different for those of who are more like weekend warriors than elite athletes.